System.IO.Path.Combine(Application.StartupPath, @"..\..\YourFile.JPG")
, VS, bin\Debug.
string path = Path.Combine(Application.StartupPath, @"..\..\YourFile.JPG");
FileStream stream = new FileStream(path, FileMode.Open, FileAccess.Read);
Image image = Image.FromStream(stream);
stream.Close();
exe, , " ", , " : " " ": , bin\Debug . :
string path = Path.Combine(Application.StartupPath, "YourFile.JPG");
VS . .