Django: method call only once when django starts

I want to initialize some variables (from the database) when starting Django.

I can get data from the database, but the problem is how should I call the initialize method. And it needs to be called only once.

I tried to search for other pages, but could not find an answer to it.

Currently, the code looks something like this:

def get_latest_dbx (request, ....):

#get data from the database

def get_latest_x (request):

get_latest_dbx (request, x, ...)

def startup (request):

get_latest_x (request)