First you need to know the codes for the regions that you are changing. You get them from the map file that you are using. Example below for a map of the USA.
To change the fill, you can configure areas when creating a map:
regionStyle: {
},
series: {
regions: [{
values: {
'US-CA': '#3e9d01',
'US-WA': '#4b93c1',
'US-TX': '#c1a14b'
},
attribute: 'fill'
}]
}
Or you can configure them on the fly (and the "value" parameter above is not needed):
$(function(){
var map = $('#map').vectorMap('get', 'mapObject');
map.series.regions[0].setValues({
'US-CA': '#3e9d01'
});
});