How to InvalidateRect with GDIPlus

All GDIPlus demo code I can find draws without invalidation. So, how do you invalidate the rectangle in the GDIPlus API when drawing with MouseMove with TImage in TScrollbox?

function NormalizeRect ( R: TRect ): TRect;
begin

  // This routine normalizes a rectangle. It makes sure that the Left,Top
  // coords are always above and to the left of the Bottom,Right coords.

  with R do
  begin

    if Left > Right then
      if Top > Bottom then
        Result := Rect ( Right, Bottom, Left, Top )
      else
        Result := Rect ( Right, Top, Left, Bottom )
    else if Top > Bottom then
      Result := Rect ( Left, Bottom, Right, Top )
    else
      Result := Rect ( Left, Top, Right, Bottom );

  end;

end;

procedure TFormMain.Image1MouseDown ( Sender: TObject; Button: TMouseButton; Shift: TShiftState; X, Y: Integer );
begin
  if Line1.Down then
  begin
    GPPointStart := MakePoint ( X, Y );
  end;
end;

procedure TFormMain.Image1MouseMove ( Sender: TObject; Shift: TShiftState; X, Y: Integer );
var
  graphics: TGPGraphics;
  pen: TGPPen;
  SolidBrush: TGPSolidBrush;
  rgbTriple: windows.RGBTRIPLE;
  iRect: TRect;
begin  
  if Line1.Down then
  begin
    if ssLeft in Shift then
    begin
      iRect := NormalizeRect ( Rect ( X, Y, Image1.Picture.Bitmap.Width, Image1.Picture.Bitmap.Height ) );
      InvalidateRect ( ScrollBox1.Handle, @iRect, TRUE );
      graphics := TGPGraphics.Create ( Image1.Picture.Bitmap.Canvas.Handle );
      graphics.Flush ( FlushIntentionFlush );
      GPPointEnd := MakePoint ( X, Y );
      rgbTriple := ColorToRGBTriple ( ColorBox1.Selected );
      pen := TGPPen.Create ( MakeColor ( StrToInt ( Alpha1.Text ), rgbTriple.rgbtRed, rgbTriple.rgbtGreen, rgbTriple.rgbtBlue )
        );
      pen.SetWidth ( StrToInt ( Size1.Text ) );
      graphics.DrawLine ( pen, GPPointStart.X, GPPointStart.Y, GPPointEnd.X, GPPointEnd.Y );
      graphics.Free;
      Image1.Refresh;
    end;
   end;
end;

It looks like this:

Using the GDIPlus library from http://www.progdigy.com since Delphi 2010.