basic approach:
determine the delay. determine the amplitude shift.
invert the signal. apply a delay. adjust the amplitude. play both audio files.
any multitrack audio application is capable of this (for example, courage, prolix or logic).
for more complex signals, you need to be smarter about your filtering, and ideally you will suppress the signals before they interfere (in Skype scripts).
, , . Logic, , . , , ?
, . , . , , .
, -?
. , ( ) , , ( , ). , () , , , .
( ) , - , , .
, . , , , . , .