Symfony2 and Doctrine2 form - failed to update foreign key in assigned objects [SOLVED]

I have profiles and studies. One person can complete a lot of research. The form is displayed correctly. There is a “Add New Study” button, and with jQuery I am adding another subform based on the data prototype, and it works well. When I submit this form with new subforms, I get a database error

Integrity constraint violation: 1048 Column 'profile_id' cannot be null 

I understand this error, but I do not know how to get rid of it. I know that I can update the research collection after binding to the controller, but I hope there is a way to configure it correctly in the annotations. When I only update objects, everything works fine.

The code:

class Profile {
    /**
     * @var integer $profileId
     *
     * @ORM\Column(name="profile_id", type="integer", nullable=false)
     * @ORM\Id
     * @ORM\GeneratedValue(strategy="IDENTITY")
     */
    private $profileId;
...
    /**
     *
     * @var Study
     * @ORM\OneToMany(targetEntity="Study", mappedBy="profile", cascade={"persist", "remove"})
     */
    private $study;

    public function __construct()
    {
        $this->study = new \Doctrine\Common\Collections\ArrayCollection();
    }
...
}

and

    class Study {
    /**
     * @var integer $studyId
     *
     * @ORM\Column(name="study_id", type="integer", nullable=false)
     * @ORM\Id
     * @ORM\GeneratedValue(strategy="IDENTITY")
     */
    private $studyId;
...
    /**
     * @var Profile
     *
     * @ORM\ManyToOne(targetEntity="Profile")
     * @ORM\JoinColumns({
     *   @ORM\JoinColumn(name="profile_id", referencedColumnName="profile_id")
     * })
     */
    private $profile;
...
}

with s (g) etters. Database Structure Substrate

CREATE TABLE IF NOT EXISTS `profile` (
  `profile_id` int(11) NOT NULL AUTO_INCREMENT,
  PRIMARY KEY (`profile_id`),
) ENGINE=InnoDB  DEFAULT CHARSET=utf8;

CREATE TABLE IF NOT EXISTS `study` (
  `study_id` int(11) NOT NULL AUTO_INCREMENT,
  `profile_id` int(11) NOT NULL,
  PRIMARY KEY (`study_id`),
) ENGINE=InnoDB  DEFAULT CHARSET=utf8;

ALTER TABLE `study`
  ADD CONSTRAINT `study_fk2` FOREIGN KEY (`profile_id`) REFERENCES `profile` (`profile_id`);

Forming buidlers:

class ProfileType extends AbstractType {

    public function buildForm(FormBuilder $builder, array $options)
    {
        $builder->add('study', 'collection', array(
                    'type' => new StudyType(),
                    'allow_add' => true,
                    'allow_delete' => true
                        )
                )
    }
...
}

and

class StudyType extends AbstractType {

    public function buildForm(FormBuilder $builder, array $options)
    {
        $builder
                ->add('city') //example field not included in above structures
    }
...
}

Javascript Part

function profileNewStudy() {
    var nr = $('[class^=profile_study_][class*=type2]').last().parent();
    nr = nr.attr('id').split('_');
    nr = nr.pop()*1 + 1;
    var proto = $('#profile_study').data('prototype');
    proto = proto.replace(/\$\$name\$\$/g, nr);
    $('#profile_study').append(proto).find('.profile_study_' + nr + ' input').val('qpa' + nr);
}

and twig template

<form action="#" method="post" {{ form_enctype(form) }}>
    {{ form_widget(form) }}
    <input type="submit" value="Zapisz"/>
</form>

NOT NULL study.profile_id, , study.profile_id = null.

@Gremo

. , :(

class Profile
    /**
     * @var Study
     * @ORM\OneToMany(targetEntity="Study", mappedBy="profile")
     */
    private $study;
class Study
    /**
     * @var Profile
     * @ORM\ManyToOne(targetEntity="Profile", inversedBy="study")
     * @ORM\JoinColumn(nullable=false, onDelete="CASCADE", referencedColumnName="profile_id")
     */
    private $profile;

, : "Alden\xxxBundle\Entity\Profile # study", entity: Alden\xxxBundle\Entity\Study @0000000073eb1a8b00000000198469ff. persist . , , "Alden\xxxxBundle\Entity\Study #__ toString()", .

, :

/**
 * @var Study
 * @ORM\OneToMany(targetEntity="Study", mappedBy="profile", cascade={"persist"})
 */
private $study;

, : SQLSTATE [23000]: : 1048 Column 'profile_id' .

:

    $request = $this->getRequest();
    $r = $this->getProfileRepository();
    $profile = $id ? $r->find($id) : new \Alden\BonBundle\Entity\Profile();
    /* @var $profile \Alden\BonBundle\Entity\Profile */
    $form = $this->createForm(new ProfileType(), $profile);
    if ($request->getMethod() == 'POST')
    {
        $form->bindRequest($request);
        if ($form->isValid())
        {
            $vacation = $profile->getVacation();
            foreach($vacation as $v) {
                $r=5;
            }
            $em = $this->getEntityManager();
            $em->persist($profile);
            $em->flush();
            //return $this->redirect($this->generateUrl('profile_list'));
        }
    }
    return array(
        'profile' => $profile,
        'form' => $form->createView()
    );

Profile , orphanRemoval foreach loop setStudies() ( @Parhs)

/**
 * @var \Doctrine\Common\Collections\ArrayCollection
 * @ORM\OneToMany(targetEntity="Study", mappedBy="profile", cascade={"ALL"}, orphanRemoval=true)
 */
private $studies;

public function __construct()
{
    $this->studies = new \Doctrine\Common\Collections\ArrayCollection();
}

/**
 * @return Doctrine\Common\Collections\Collection
 */
public function getStudies()
{
    return $this->studies;
}

public function setStudies($studies)
{
    foreach ($studies as $v)
    {
        if (is_null($v->getProfile()))
        {
            $v->setProfile($this);
        }
    }
    $this->studies = $studies;
}

/**
 * @var Profile
 * @ORM\ManyToOne(targetEntity="Profile", inversedBy="studies")
 * @ORM\JoinColumn(name="profile_id", nullable=false, onDelete="CASCADE", referencedColumnName="profile_id")
 */
private $profile;

.